Mc4r in postnatal mouse PVN
Evgenii Tretiakov
2021-05-20
Last updated: 2021-05-20
Checks: 7 0
Knit directory: mc4r/
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Published subset of adult hypothalamic data (Nature + Cell datasets) in UMAP (cells similarity) space
Density of expression for MC-R gene family in UMAP space
Zoom into area of highest density of Mc4r expressing cells in UMAP space (PNe of PVN)
Age dynamic
| term | Mc4r | Trh |
|---|---|---|
| Dgkg | 0.35 | 0.43 |
| Lin37 | 0.33 | 0.28 |
| Cluh | 0.28 | 0.26 |
| 1700086L19Rik | 0.28 | 0.28 |
| Vstm2l | 0.27 | 0.33 |
| Polr1c | 0.27 | 0.25 |
| Pkib | 0.26 | 0.26 |
| Pura | 0.25 | 0.31 |
| Brinp3 | 0.25 | 0.43 |
| Dgat2 | 0.25 | 0.35 |
| Ccdc181 | 0.25 | 0.24 |
| Sel1l3 | 0.23 | 0.30 |
| Slc1a4 | 0.23 | 0.31 |
| Saxo2 | 0.22 | 0.27 |
| Fam73a | 0.22 | 0.24 |
| Tmem59l | 0.21 | 0.24 |
| Fh1 | 0.21 | 0.44 |
| Cntn4 | 0.21 | 0.45 |
| Cntnap3 | 0.20 | 0.52 |
| Lgi1 | 0.20 | 0.23 |
| Dgkb | 0.20 | 0.46 |
| Arhgap26 | 0.20 | 0.35 |
| Purb | 0.20 | 0.30 |
| Hdhd2 | 0.19 | 0.33 |
| Nudt9 | 0.19 | 0.51 |
| Mdga2 | 0.19 | 0.36 |
| Csgalnact1 | 0.19 | 0.39 |
| Csmd3 | 0.19 | 0.30 |
| Nfu1 | 0.19 | 0.27 |
| Tcta | 0.19 | 0.29 |
| Nfia | 0.18 | 0.26 |
| Mbnl2 | 0.18 | 0.56 |
| Brk1 | 0.18 | 0.24 |
| Mrpl55 | 0.18 | 0.37 |
| Htr4 | 0.18 | 0.32 |
| Mlip | 0.18 | 0.27 |
| Smdt1 | 0.18 | 0.33 |
| Ostm1 | 0.18 | 0.23 |
| Snrk | 0.18 | 0.31 |
| Fam107a | 0.18 | 0.26 |
| Fam183b | 0.18 | 0.29 |
| Ubb | 0.18 | 0.51 |
| Prkg1 | 0.18 | 0.53 |
| Cycs | 0.17 | 0.46 |
| Psmg4 | 0.17 | 0.26 |
| Chchd10 | 0.17 | 0.39 |
| Pld3 | 0.17 | 0.27 |
| Rasa3 | 0.17 | 0.28 |
| St6galnac6 | 0.17 | 0.25 |
| Prdx5 | 0.17 | 0.26 |
| Tmem132b | 0.16 | 0.49 |
| Stard7 | 0.16 | 0.26 |
| 2010300C02Rik | 0.16 | 0.34 |
| Coq7 | 0.16 | 0.30 |
| Pdzrn4 | 0.16 | 0.36 |
| 2310039H08Rik | 0.15 | 0.29 |
| Mkrn1 | 0.15 | 0.23 |
| Ptprn | 0.15 | 0.26 |
| Hmgn3 | 0.15 | 0.24 |
| Wrb | 0.15 | 0.25 |
| Rpp25l | 0.15 | 0.36 |
| Cuta | 0.15 | 0.24 |
| Mpc1 | 0.15 | 0.28 |
| Ddit3 | 0.15 | 0.23 |
| Slc10a6 | 0.15 | 0.35 |
| Rab27a | 0.15 | 0.25 |
| mt-Nd6 | 0.15 | 0.28 |
| Gpr101 | 0.14 | 0.29 |
| Oxct1 | 0.14 | 0.26 |
| Kars | 0.14 | 0.25 |
| Greb1l | 0.14 | 0.33 |
| Flywch1 | 0.14 | 0.32 |
| Gpx4 | 0.14 | 0.50 |
| Cyb561 | 0.14 | 0.27 |
| Tbc1d20 | 0.14 | 0.23 |
| Necab2 | 0.14 | 0.34 |
| Dync1i1 | 0.14 | 0.46 |
| Atp5sl | 0.14 | 0.26 |
| Rxrg | 0.14 | 0.28 |
| Mrpl27 | 0.14 | 0.28 |
| Naa20 | 0.14 | 0.24 |
| Tmx4 | 0.14 | 0.29 |
| Sfmbt2 | 0.13 | 0.24 |
| Pnkd | 0.13 | 0.24 |
| Nsmf | 0.13 | 0.26 |
| Dlg1 | 0.13 | 0.26 |
| Syt5 | 0.13 | 0.29 |
| Ndufa7 | 0.13 | 0.51 |
| Rogdi | 0.13 | 0.26 |
| Ndufb9 | 0.13 | 0.46 |
| Ppargc1a | 0.13 | 0.29 |
| Htr7 | 0.13 | 0.34 |
| Gm4876 | 0.13 | 0.29 |
| Cdh13 | 0.13 | 0.24 |
| Ndufa8 | 0.13 | 0.32 |
| Psma5 | 0.13 | 0.31 |
| Mpc2 | 0.13 | 0.32 |
| Efr3a | 0.12 | 0.25 |
| Pcbd1 | 0.12 | 0.26 |
| Macrod1 | 0.12 | 0.27 |
| Mrfap1 | 0.12 | 0.38 |
| Tef | 0.12 | 0.23 |
| Phb | 0.12 | 0.26 |
| Rundc1 | 0.12 | 0.24 |
| Kcnc2 | 0.12 | 0.31 |
| Phyhip | 0.12 | 0.28 |
| Dtd1 | 0.12 | 0.25 |
| Gfra4 | 0.12 | 0.23 |
| Mdh2 | 0.12 | 0.48 |
| Bex1 | 0.12 | 0.32 |
| Zkscan16 | 0.12 | 0.35 |
| Ppp1r17 | 0.12 | 0.37 |
| Gdi1 | 0.12 | 0.27 |
| Mdh1 | 0.12 | 0.27 |
| 2010107E04Rik | 0.12 | 0.37 |
| Ckmt1 | 0.12 | 0.28 |
| Eno2 | 0.12 | 0.34 |
| Mrps15 | 0.12 | 0.27 |
| Rtn1 | 0.11 | 0.25 |
| Mzt1 | 0.11 | 0.26 |
| Srm | 0.11 | 0.24 |
| Gstp2 | 0.11 | 0.31 |
| Thrb | 0.11 | 0.26 |
| Vps4a | 0.11 | 0.24 |
| Slc22a17 | 0.11 | 0.25 |
| Pacrg | 0.11 | 0.28 |
| Asic2 | 0.11 | 0.35 |
| Riiad1 | 0.11 | 0.26 |
| Atp6v1f | 0.11 | 0.40 |
| Gm42418 | -0.06 | -0.16 |
| Tcf12 | -0.06 | -0.15 |
| Epha6 | -0.06 | -0.15 |
| Ssbp2 | -0.06 | -0.14 |
| Kctd16 | -0.06 | -0.16 |
| Hmbox1 | -0.06 | -0.17 |
| Ythdf2 | -0.06 | -0.14 |
| Hnrnpk | -0.06 | -0.24 |
| Clasp1 | -0.06 | -0.15 |
| Zfp804a | -0.06 | -0.15 |
| Sox11 | -0.06 | -0.25 |
| Dlgap3 | -0.06 | -0.11 |
| mt-Co3 | -0.07 | -0.18 |
| Ebf3 | -0.07 | -0.12 |
| Nova1 | -0.07 | -0.14 |
| Zc3h7b | -0.07 | -0.11 |
| mt-Nd3 | -0.07 | -0.15 |
| Lmnb1 | -0.07 | -0.14 |
| Actr3 | -0.07 | -0.14 |
| Elavl2 | -0.07 | -0.21 |
| Med13l | -0.07 | -0.11 |
| Srrm2 | -0.07 | -0.20 |
| Psmb6 | -0.07 | -0.14 |
| Ogt | -0.07 | -0.12 |
| Scg2 | -0.07 | -0.14 |
| Rbm3 | -0.07 | -0.12 |
| Ctsb | -0.07 | -0.11 |
| Gm26917 | -0.07 | -0.34 |
| Ctnna2 | -0.07 | -0.22 |
| Fnbp1l | -0.07 | -0.19 |
| Resp18 | -0.07 | -0.15 |
| Sox4 | -0.07 | -0.12 |
| Ubc | -0.07 | -0.12 |
| Ina | -0.08 | -0.12 |
| Stmn1 | -0.08 | -0.14 |
| Btbd9 | -0.08 | -0.15 |
| Cdc37 | -0.08 | -0.11 |
| Kcnh8 | -0.08 | -0.15 |
| Hnrnpab | -0.08 | -0.12 |
| Hn1 | -0.08 | -0.18 |
| Trio | -0.08 | -0.14 |
| Zcchc11 | -0.08 | -0.15 |
| Cep78 | -0.08 | -0.12 |
| Rasa1 | -0.08 | -0.12 |
| Npas3 | -0.08 | -0.15 |
| Shank1 | -0.08 | -0.15 |
| Plppr3 | -0.08 | -0.17 |
| Runx1t1 | -0.08 | -0.23 |
| Dip2b | -0.08 | -0.13 |
| Tnrc6c | -0.08 | -0.11 |
| Nrp1 | -0.08 | -0.13 |
| Dusp8 | -0.08 | -0.14 |
| Astn2 | -0.08 | -0.18 |
| Fign | -0.08 | -0.16 |
| Ddx5 | -0.08 | -0.24 |
| Smarce1 | -0.08 | -0.14 |
| Gm26848 | -0.08 | -0.11 |
| Rbm42 | -0.08 | -0.12 |
| Pds5a | -0.08 | -0.16 |
| Pde3b | -0.08 | -0.12 |
| Wdr70 | -0.08 | -0.12 |
| Zfand5 | -0.08 | -0.12 |
| Strip1 | -0.08 | -0.11 |
| Tmpo | -0.08 | -0.11 |
| Phc2 | -0.08 | -0.13 |
| Eif2s2 | -0.08 | -0.12 |
| Slc1a2 | -0.09 | -0.12 |
| Rad21 | -0.09 | -0.11 |
| Tubb5 | -0.09 | -0.34 |
| Kalrn | -0.09 | -0.29 |
| Grik3 | -0.09 | -0.12 |
| 1700025G04Rik | -0.09 | -0.11 |
| Snf8 | -0.09 | -0.11 |
| Nkain3 | -0.09 | -0.22 |
| Ubxn7 | -0.09 | -0.12 |
| Sox5 | -0.09 | -0.15 |
| E130308A19Rik | -0.09 | -0.17 |
| Zfp462 | -0.09 | -0.11 |
| Slc38a10 | -0.09 | -0.12 |
| Zswim6 | -0.09 | -0.14 |
| Inpp4b | -0.09 | -0.12 |
| Alk | -0.09 | -0.16 |
| Mapk6 | -0.09 | -0.11 |
| Zfp704 | -0.10 | -0.14 |
| Fgf13 | -0.10 | -0.11 |
| Stag2 | -0.10 | -0.11 |
| Zfp207 | -0.10 | -0.13 |
| Klhl29 | -0.10 | -0.11 |
| Anp32a | -0.10 | -0.14 |
| Dock7 | -0.10 | -0.18 |
| Map4 | -0.10 | -0.16 |
| Rab11a | -0.10 | -0.13 |
| Wnk1 | -0.10 | -0.13 |
| Kmt2e | -0.10 | -0.14 |
| Srgap3 | -0.10 | -0.12 |
| Slc8a1 | -0.10 | -0.14 |
| Zfp57 | -0.10 | -0.14 |
| Dpp10 | -0.11 | -0.13 |
| Arid2 | -0.11 | -0.14 |
| Tcf20 | -0.11 | -0.18 |
| mt-Nd1 | -0.11 | -0.19 |
| Hmgcr | -0.11 | -0.12 |
| Arid1a | -0.11 | -0.12 |
| Dzip1 | -0.11 | -0.13 |
| Klf12 | -0.11 | -0.15 |
| Kcnh7 | -0.11 | -0.15 |
| Tmem163 | -0.11 | -0.14 |
| Erbb4 | -0.12 | -0.16 |
| Il1rapl1 | -0.12 | -0.18 |
| Fam19a2 | -0.12 | -0.20 |
| Gpc6 | -0.12 | -0.20 |
| Dlk1 | -0.12 | -0.26 |
| Lingo2 | -0.12 | -0.16 |
| Auts2 | -0.12 | -0.38 |
| Robo1 | -0.13 | -0.26 |
| D630045J12Rik | -0.13 | -0.14 |
| Celf2 | -0.13 | -0.23 |
| Ncam2 | -0.13 | -0.30 |
| Rbfox1 | -0.13 | -0.16 |
| Ccser1 | -0.14 | -0.23 |
| Hnrnpc | -0.14 | -0.20 |
| Slit2 | -0.15 | -0.25 |
| Sntg1 | -0.15 | -0.19 |
| Kcnip1 | -0.16 | -0.18 |
| Unc5d | -0.17 | -0.24 |
| Elavl3 | -0.18 | -0.14 |
| Xkr4 | -0.18 | -0.18 |
| Cadm2 | -0.18 | -0.32 |
| Version | Author | Date |
|---|---|---|
| acde8ba | EugOT | 2021-05-19 |
| Version | Author | Date |
|---|---|---|
| acde8ba | EugOT | 2021-05-19 |
Gene Combinations
| Version | Author | Date |
|---|---|---|
| acde8ba | EugOT | 2021-05-19 |
| Version | Author | Date |
|---|---|---|
| acde8ba | EugOT | 2021-05-19 |
| Version | Author | Date |
|---|---|---|
| acde8ba | EugOT | 2021-05-19 |
| Version | Author | Date |
|---|---|---|
| acde8ba | EugOT | 2021-05-19 |
R version 4.1.0 (2021-05-18)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: Ubuntu 20.10
Matrix products: default
BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.10.so
locale:
[1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
[3] LC_TIME=de_AT.UTF-8 LC_COLLATE=en_US.UTF-8
[5] LC_MONETARY=de_AT.UTF-8 LC_MESSAGES=en_US.UTF-8
[7] LC_PAPER=de_AT.UTF-8 LC_NAME=C
[9] LC_ADDRESS=C LC_TELEPHONE=C
[11] LC_MEASUREMENT=de_AT.UTF-8 LC_IDENTIFICATION=C
attached base packages:
[1] stats graphics grDevices datasets utils methods base
other attached packages:
[1] Nebulosa_1.2.0 patchwork_1.1.1 UpSetR_1.4.0
[4] SeuratDisk_0.0.0.9019 SeuratWrappers_0.3.0 SeuratObject_4.0.1
[7] Seurat_4.0.1 kableExtra_1.3.4 future_1.21.0
[10] magrittr_2.0.1 forcats_0.5.1 stringr_1.4.0
[13] dplyr_1.0.6 purrr_0.3.4 readr_1.4.0
[16] tidyr_1.1.3 tibble_3.1.2 ggplot2_3.3.3
[19] tidyverse_1.3.1 here_1.0.1 workflowr_1.6.2
loaded via a namespace (and not attached):
[1] utf8_1.2.1 reticulate_1.20
[3] ks_1.12.0 tidyselect_1.1.1
[5] htmlwidgets_1.5.3 grid_4.1.0
[7] Rtsne_0.15 munsell_0.5.0
[9] codetools_0.2-17 ica_1.0-2
[11] miniUI_0.1.1.1 withr_2.4.2
[13] colorspace_2.0-1 Biobase_2.52.0
[15] corrr_0.4.3 highr_0.9
[17] knitr_1.33 rstudioapi_0.13
[19] stats4_4.1.0 SingleCellExperiment_1.14.0
[21] ROCR_1.0-11 tensor_1.5
[23] listenv_0.8.0 labeling_0.4.2
[25] MatrixGenerics_1.4.0 git2r_0.28.0
[27] GenomeInfoDbData_1.2.6 polyclip_1.10-0
[29] farver_2.1.0 bit64_4.0.5
[31] rprojroot_2.0.2 parallelly_1.25.0
[33] vctrs_0.3.8 generics_0.1.0
[35] xfun_0.23 R6_2.5.0
[37] GenomeInfoDb_1.28.0 rsvd_1.0.5
[39] hdf5r_1.3.3 bitops_1.0-7
[41] spatstat.utils_2.1-0 DelayedArray_0.18.0
[43] assertthat_0.2.1 promises_1.2.0.1
[45] scales_1.1.1 gtable_0.3.0
[47] globals_0.14.0 goftest_1.2-2
[49] rlang_0.4.11 systemfonts_1.0.2
[51] splines_4.1.0 lazyeval_0.2.2
[53] spatstat.geom_2.1-0 broom_0.7.6
[55] BiocManager_1.30.15 yaml_2.2.1
[57] reshape2_1.4.4 abind_1.4-5
[59] modelr_0.1.8 backports_1.2.1
[61] httpuv_1.6.1 tools_4.1.0
[63] ellipsis_0.3.2 spatstat.core_2.1-2
[65] jquerylib_0.1.4 RColorBrewer_1.1-2
[67] BiocGenerics_0.38.0 ggridges_0.5.3
[69] Rcpp_1.0.6 plyr_1.8.6
[71] zlibbioc_1.38.0 RCurl_1.98-1.3
[73] rpart_4.1-15 deldir_0.2-10
[75] pbapply_1.4-3 cowplot_1.1.1
[77] S4Vectors_0.30.0 zoo_1.8-9
[79] SummarizedExperiment_1.22.0 haven_2.4.1
[81] ggrepel_0.9.1 cluster_2.1.2
[83] fs_1.5.0 data.table_1.14.0
[85] scattermore_0.7 lmtest_0.9-38
[87] reprex_2.0.0 RANN_2.6.1
[89] mvtnorm_1.1-1 whisker_0.4
[91] fitdistrplus_1.1-3 matrixStats_0.58.0
[93] hms_1.1.0 mime_0.10
[95] evaluate_0.14 xtable_1.8-4
[97] mclust_5.4.7 readxl_1.3.1
[99] IRanges_2.26.0 gridExtra_2.3
[101] compiler_4.1.0 KernSmooth_2.23-20
[103] crayon_1.4.1 htmltools_0.5.1.1
[105] mgcv_1.8-35 later_1.2.0
[107] lubridate_1.7.10 DBI_1.1.1
[109] dbplyr_2.1.1 MASS_7.3-54
[111] Matrix_1.3-3 cli_2.5.0
[113] parallel_4.1.0 igraph_1.2.6
[115] GenomicRanges_1.44.0 pkgconfig_2.0.3
[117] plotly_4.9.3 spatstat.sparse_2.0-0
[119] xml2_1.3.2 svglite_2.0.0
[121] bslib_0.2.5.1 webshot_0.5.2
[123] XVector_0.32.0 rvest_1.0.0
[125] digest_0.6.27 sctransform_0.3.2
[127] RcppAnnoy_0.0.18 spatstat.data_2.1-0
[129] rmarkdown_2.8 cellranger_1.1.0
[131] leiden_0.3.7 uwot_0.1.10
[133] shiny_1.6.0 lifecycle_1.0.0
[135] nlme_3.1-152 jsonlite_1.7.2
[137] viridisLite_0.4.0 fansi_0.4.2
[139] pillar_1.6.1 lattice_0.20-44
[141] fastmap_1.1.0 httr_1.4.2
[143] survival_3.2-11 glue_1.4.2
[145] remotes_2.3.0 png_0.1-7
[147] bit_4.0.4 stringi_1.6.2
[149] sass_0.4.0 renv_0.13.2
[151] irlba_2.3.3 future.apply_1.7.0